apalutamide will lessen the extent or outcome of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Keep away from or Use Alternate Drug. Coadministration of apalutamide, a powerful CYP3A4 inducer, with medication which might be CYP3A4 substrates may end up in reduced exposure to these medicines.Making use of this drug, even as pres